As of 2018, ACLF has impacted 4.5 million Americans and has caused over 51,000 deaths in 2020 alone [1]
ACLF is also a disease that progresses quickly, with 25% of patients dying within 1 month of being diagnosed and 40% dying within 3 months [2]. Therefore, it is critical to treat ACLF as soon as possible, preferably before 1 month post-diagnosis in order to increase chances of survival.