Medically speaking LQTS1 happens suddenly and can cause dangerous arrhythmias. It can lead to early afterdepolarization if block of IKs is more than 80%. Sudden Cardiac Arrest (SCA) is possible as is fainting due to a lack of oxygen to the brain, especially during times of emotional stress.

LQT1 symptoms typically occurs more frequently in women than men with LQT1, although during childhood it occurs more often in men than in women. Although there are cases of Silent Long QT Syndrome where no noticeable symptoms are produced beyond the electrical variance. The actual change in the ECG pattern can be seen in the graph below.

How does diagnosis work?: After it is suspected several ECG tests are done over a period of days or weeks or patients may have to wear a holter monitor, and a Medical History & Physical Exam are performed. Patients are asked about symptoms of an abnormal heart rhythm & whether patient’s family has any history of LQTS and what other prescribed medicines they take. Knowledge of Inherited LQTS will help the patient and their doctor plan their treatment & decide which lifestyle changes the patient should make.