Who Are We?:

Salwa Anam

• Research on Background, Mutation, Channel Structure

Juan Bastidas

• Background Research, Finding Mutation Values, Channel Structure, and Presentation/Presenting

Vincent Bhandal

• Research on Treatments, Channel Conformation, and Background

Peter Czechowicz

• Initial Background/Genetic Research, Helped with Treatment Research and Slides

Makhjoom Ferdous

• Background, Mutation, Channel Function

Daniel Gibbons

• Matlab and Website

William Hackett

• Matlab, Website, and Presentation/Presenting

Nestor Ibanez

• Background Research,  Mutation Values, and Problem Research for Genetic and Human

Ridhwan Mohammad

• Research on Background, Finding Mutation Values, Slides on Channel Function

Ashley Zerbe

• Initial and Treatment Research, Helped with Treatment Slides

 

 

Our Sources:

1. “Long QT Syndrome Knowledge Base.” : Clinical Characteristics. The Children’s Hospital of Philadelphia Research Institute, n.d. Web. 07 May 2015.
2. The cardiac IKs channel, complex indeed. J. D.Osteen – K. J.Sampson – R. S.Kass – Proceedings of the National Academy of  Sciences – 2010
3. “What Are the Signs and Symptoms of Long QT Syndrome?” – NHLBI, NIH. N.p., n.d. Web. 07 May 2015.
4. Jespersen, Thomas, Morten Grunnet, and Soren P. Olesen. “The KCNQ1 Potassium Channel: From Gene to Physiological Function.” Physiology 20.6 (2005): 408-16. Print.
5. Kaczmarek, L. K., and E. M. Blumenthal. “Properties and Regulation of the MinK Potassium Channel Protein.” Physiological Reviews 77.3 (1997): n. pag. Web. 7 May 2015.
6. “Genetics Home Reference.” – Your Guide to Understanding Genetic Conditions. Web. 7 May 2015.
7. “What Causes Long QT Syndrome?” – NHLBI, NIH. Web. 7 May 2015.
8. Levine, E., S. Z. Rosero, A. S. Budzikowski, A. J. Moss, W. Zareba, and J. P. Daubert. “Congenital Long QT Syndrome: Considerations for Primary Care Physicians.” Cleveland Clinic Journal of Medicine (2008): 591-600. Print.
9. Jespersen, T. “The KCNQ1 Potassium Channel: From Gene to Physiological Function.” Physiology (2005): 408-16. Print.
10. Bartos, Daniel C., Sabine Duchatelet, Don E. Burgess, Didier Klug, Isabelle Denjoy, Rachel Peat, Jean-Marc Lupoglazoff, Véronique Fressart, Myriam Berthet, Michael J. Ackerman, Craig T. January, Pascale Guicheney, and Brian P. Delisle. “R231C Mutation in KCNQ1 Causes Long QT Syndrome Type 1 and Familial Atrial Fibrillation.” Heart Rhythm: 48-55. Print.
11. “Heart Sisters.” Heart Sisters. Web. 7 May 2015.
12. Eldstrom, J., H. Xu, D. Werry, C. Kang, M. E. Loewen, A. Degenhardt, S. Sanatani, G. F. Tibbits, C. Sanders, and D. Fedida. “Mechanistic Basis for LQT1 Caused by S3 Mutations in the KCNQ1 Subunit of IKs.” The Journal of General Physiology (2010): 433-48. Print.
13. Ali A Sovari, M., FACP; Chief Editor: Jeffrey N Rottman, MD, Long QT Syndrome Treatment & Management. Medscape,
14. Dr Ananya Mandal, M. Treatment of Long QT Syndrome (LQTS). 2012
15.   James P. Daubert, M.A.O.G., MD, PhD†; Kent R. Nilsson, MD, Novel Insights Into Beta-Blocker Therapy for Long QT
16.     How Is Long QT Syndrome Treated? 2011.
17.      Chockalingam P1, C.L., Girardengo G, Johnson JN, Harris KM, van der Heijden JF, Hauer RN, Beckmann BM,Long QT Syndrome: A Guide for Patients and Health Care Providers. 2008.Spazzolini C, Rordorf R, Rydberg A, Clur SA, Fischer M, van den Heuvel F, Kääb S, Blom NA, Ackerman MJ, Schwartz, PJ., Wilde AA., Not all beta-blockers are equal in the management of long QT syndrome types 1 and 2: higher recurrence of events under metoprolol.
18. J Am Coll Cardiol. , 2012. 60(20): p. 2092-9. Syndromes. J Am Coll Cardiol., 2012. 60(20): p. 2100-2102.
19.      E.O. Udo, H.F.B., […], and A.A.M. Wilde, Not just any ICD device in patients with long-QT syndrome. Neth Heart J. , 2007. 15(12): p. 418–421.
20.      Shimizu, W., The long QT syndrome: Therapeutic implications of a genetic diagnosis. Cardiovascular Research, 2005: p.347-356.2014.