Current Research at SUNY Stony Brook University

Human T-cell stained with Phalloidin and NucBlue. Phalloidin stains actin filaments and NucBlue stains the nucleus.

PI: Dr. Mei Lin Chan

My current research focuses on the potential use of low intensity vibration (LIV) to stimulate faster cell growth of human T-cells. LIV is a relatively low cost technique that has great potential in the field of biomedical research because and it is also observed that different cell types are impacted by such mechanical simulations. Rapid expansion of human T-cells will be useful in medical applications like CAR T-cell therapy in cancer treatment.

 

Barabino Laboratory at CUNY City College of New York

Presentation at ABRCMS Conference, Phoenix, Arizona

Research Assistant under PIs: Dr. Yueh Hsun Yang & Dr. Gilda Barabino

Developed protocols to decellularize extracellular matrix of native cartilage. Conducted studies to evaluate effects of aging on human mesenchymal stem cells using flow cytometry and qPCR techniques

Simpson Laboratory at Memorial Sloan Kettering Cancer Center

Presentation at MSK Engineering Summer Program

Research Intern under PI: Dr. Amber L. Simpson

Completed a project on predicting histologic growth patterns of liver cancer from preoperative CT imaging via machine learning using radiomics. The goal was to develop a method to diagnose what type of liver cancer the patient had before a liver resection. It is known that different types of liver cancer are more receptive to different types of treatment therefore knowing the type of cancer before surgery would save the patient from doing a labor intensive surgery.

Gerber Laboratory at SUNY Downstate Medical Center

Third place at ACTSO NYC with this project (2015)

Medical Intern under Dr. Donald A. Gerber

Investigated the causes of drug-induced Lupus erythematosus through in vitro procedures involving biochemistry. A small set of lupus patients develop the disease after taking certain medication for a long period of time due to unknown reasons. My work demonstrated a potential explanation why the drug, Hydralazine, may cause such reactions in such patients through certain chemical reactions in the body.

Publication

Yueh-Hsun Kevin Yang, Courtney R. Ogando, Carmine Wang See, Tsui-Yun Chang and Gilda Barabino. Changes in Phenotype and Differentiation Potential of Human Mesenchymal Stem Cells Aging In Vitro. Stem Cell Research & Therapy. 2018. 9:131.

Conference Presentation

Carmine Wang See, Tsuo-Yun Chang, Yueh-Hsun Yang, Gilda Barabino. Variation in Surface Marker and Gene Expression of In Vitro Aging Human Mesenchymal Stem Cells. Abstract #E-099. Presented at the Annual Biomedical Research Conference for Minority Students (ABRCMS), Phoenix, Arizona. 2017

Skills

Laboratory: Stem cell culture, flow cytometry, qPCR, protein assays, fluorescent and light microscopy
Application: Microsoft Word, Excel, and PowerPoint
Programming Languages: Matlab, Python, C++
Design Software: Solidworks