The molecular mechanisms that control oligodendrocyte development and myelination

• Understanding how the extracellular matrix regulates oligodendroglial signal transduction
• Discovering that oligodendrogenesis is aberrant in Duchenne muscular dystrophy
• Exploring the link between oligodendroglial metabolism and myelinogenic capacity

Myelin repair and Multiple Sclerosis

• Repurposing the diabetes drug Metformin to promote myelin repair
• Examining the connection between pregnancy and MS: the role of circulating extracellular vesicles

Assembly and function of the subventricular zone neural stem cell niche

• Dissecting the role of the extracellular matrix and its receptors in the development of ependymal cells
• Uncovering the molecular mechanisms that control stem cell niche function and output