Architect: Mitchell/Giurgola Architects

Gábor Balázsi   Quantitative Systems and Synthetic Biology.
My lab studies the genotype-phenotype connection by using synthetic gene circuits to precisely control gene expression in yeast and mammalian cells, and to study single cell- and cell population-level phenotypes such as survival during drug treatment and phenotypes characteristic of cancer progression. We develop predictive quantitative models of the genotype-phenotype connection, and then test the predictions experimentally, hoping to understand control mechanisms from genes to cells to cell populations.

Ken Dill   Physics of proteins, biological cells, and water
My research group is interested in the physics of how proteins fold; the microscopic origins of the unusual physical properties of water; the foundations and applications of variational entropy-based principles in statistical physics; and how the laws of physics constrain and enable the biological properties and evolution of cells.

Sasha Levy   Evolution, Systems Biology, Technological development
My lab develops technologies using random DNA barcodes and next-generation sequencing to quantitatively study the behavior of millions of small lineages in large cell populations. We use these tools to understand how cell populations, such as microbial pathogens or cancer, evolve; how environmental fluctuations shape evolutionary strategies; how genetic and protein-protein interaction networks change across environments; and how genetic architecture constrains the adaptive process.