Deniz Erezyilmaz Functional Evolutionary Genomics
My research seeks the genetic changes that facilitate divergence between species. I use high throughput genomics to identify evolved loci, and molecular genetics to learn how the underlying genetic changes contribute to separation of species. My ultimate goal is to learn how genomes limit or enable adaptive change.
Bernadette Holdener Interactions Between Early Embryonic Tissues
Nancy Hollingsworth
My lab studies the role that phosphorylation plays in the regulation of meiotic chromosome behavior during meiosis in budding yeast. One of the tools that we have used to monitor recombination genome wide is to sequence the DNA from the four haploid products of a single meiosis to map the number and distribution of all of the crossover and noncrossover events that occur in a single meiosis.
Wali Karzai Post-transcriptional Regulation of Gene Expression
Sasha Levy Evolution, Systems Biology, Technological development
My lab develops technologies using random DNA barcodes and next-generation sequencing to quantitatively study the behavior of millions of small lineages in large cell populations. We use these tools to understand how cell populations, such as microbial pathogens or cancer, evolve; how environmental fluctuations shape evolutionary strategies; how genetic and protein-protein interaction networks change across environments; and how genetic architecture constrains the adaptive process.
Q. Alison Liu Global warming and epigenomes
David Matus Cell Invasion