People


David Q Matus, PhD
Assistant Professor
Department of Biochemistry and Cell Biology
Stony Brook University
Stony Brook, NY 11794-5215
631-632-8014
david.matus AT stonybrook.edu

 

 

WanZ_webWan Zhang

Lab Manager and Research Technician

 

 

 

 

 

 

 

Nicholas Palmisano, PhD

Postdoctoral Fellow in the Matus and Martin Lab

My work focuses on understanding how membrane trafficking events, such as endocytosis and exocytosis, mediate AC invasion. Specifically, I am interested in how endocytic compartments mobilize during AC invasion. Currently, I am investigating how the effector protein of the small GTPase, RAB-10, functions in AC invasion using both genetic and cell biological approaches.

 

Rebecca Adikes, PhD

Postdoctoral Fellow

I am currently investigating algal cell migration and invasion in the spotted salamander embryo. The work is a collaborative effort with Drs. Ryan Kerney, Solange Dumel and  John Burns. I am also investigating the role of cell invasion and migration during C. elegans development.

 

Abraham Kohrman

PhD Candidate in Genetics

I am broadly interested in cell cycle regulation of morphogenetic behavior. Specifically, I am currently focused on optimization of a live cell cycle state biosensor for use in C. elegans and other research organisms. I am also interested in how cell cycle state regulation impinges upon morphogenetic behaviors, such as C. elegans anchor cell invasion into the vulval epithelium.

 

Taylor Medwig-Kinney

PhD Candidate in Genetics

My research interests lie in the field of Genetic Epidemiology; I am particularly interested in exploring the evolution and epigenetic regulation of genes that contribute to human morbidity.  Currently, I am investigating the interactions among transcription factors in C. elegans that are known to regulate cell invasion, a behavior relevant to cancer metastasis.

 

Jayson “Jay” Smith

Turner Fellow and PhD Candidate in Genetics

I am broadly interested in trying to understand how chromatin state interfaces with regulation of cell invasive behavior. I am using C. elegans anchor cell invasion to identify the suite of chromatin modifiers that regulate invasion, with the hopes of identifying new therapeutic targets to limit the lethality associated with invasive pathologies, such as cancer metastasis.

 

 

Michael Martinez

MD/PhD Student in Molecular and Cellular Pharmacology

I have a keen interest in understanding the molecular and cellular mechanisms underlying cell invasive behavior. Presently, I am investigating the effects of clinically approved cell cycle inhibitors on anchor cell (AC) invasion, which is an important step in the development of the C. elegans reproductive tract.

 

 

Kenny Chiu

Undergraduate Student | Wesleyan University Class of 2019

I am interested in building new tools to study gene regulation during C. elegans anchor cell invasion using CRISPR/Cas9 genome engineering.

 

Rumana Rahman

Undergraduate Student | Stony Brook University Class of 2020

I am interested in the expression of invasive genes during AC invasion in C. elegans. I am currently investigating the effects of gene-knockouts in cell invasion through basement membrane, and I am also working on building a tool to visualize C. elegans under fluorescent imaging.

 

 

Matus Lab Alumni

 

Postdoctoral Researchers:

Antonio Herrera, PhD

Graduate Students:

Robert Morabito (PhD Candidate, Benjamin Martin Lab)

Nuri Kim (MD/PhD Candidate, Jessica Seeliger Lab)

Mana Chandhok (Cambridge Healthtech Institute)

Master’s Students:

Simeiyun “May” Liu (PhD Student, UC Santa Cruz)

Medical Students:

Digna Nosike

Postbaccalaureate Researchers:

Ayesha Saad

Undergraduate Students:

Yee Man Li

Bria Midgette

High School Students:

Stephanie Hu

Angie Jang

Matthew Weltmann

Ella Feiner (Undergraduate Student, Princeton University)

Sydney Bracht (Undergraduate Student, Johns Hopkins University)

Mit Patel (Undergraduate Student, Harvard University)

Kiera Alventosa (Undergraduate Student, Amherst College)

 

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