Publications

JOURNAL PUBLICATIONS (Google Scholar | ResearchGate):

  1. Li, Y., Moore, R.*, Guinn, M.*, & Bleris, L. (2012). Transcription activator-like effector hybrids for conditional control and rewiring of chromosomal transgene expression. Scientific Reports 2: 897, https://doi.org/10.1038/srep00897 (*equal contribution)
  2. Guinn, M. & Bleris, L. (2014). Biological 2-Input Decoder Circuit in Human Cells. ACS Synthetic Biology. https://doi.org/10.1021/sb4001596
  3. Ehrhardt, K.*, Guinn, M. T.*, Quarton, T., Zhang, M., & Bleris, L. (2015). Reconfigurable hybrid interface for molecular marker diagnostics and in-situ reporting. Biosensors and Bioelectronics, Volume 74, 15 December 2015, Pages 744-750, ISSN 0956-5663, https://doi.org/10.1016/j.bios.2015.07.035 (*equal contribution)
  4. Zañudo, JGT, Guinn, M.T.,Farquhar, K., Szenk, M., Steinway, S.N., Balazsi, G., & Albert, R. (2019). Towards control of cellular decision-making networks in the epithelial-to-mesenchymal transition. Physical Biology. Physical Biology 2019 Jan 17. https://doi.org/10.1088/1478-3975/aaffa1
  5. Guinn, M.T. & Balazsi, G. (2019). Noise-Reducing Optogenetic Negative-Feedback Gene Circuits in Human Cells. Nucleic Acids Research, gkz556, https://doi.org/10.1093/nar/gkz556
  6. Guinn, M.T. & Balazsi, G. (2019). A new resource for future and current quantitative biologists. The Quarterly Review of Biology, Volume 94, Issue 4, December 2019, https://www.journals.uchicago.edu/doi/abs/10.1086/706383.

CONFERENCE ABSTRACTS, SEMINARS, & PRESENTATIONS:

  1. Brasseaux, C., Golynskiy, Guinn, M., Sant, S., Bhattatiry, M., Bhattatiry, N., & Flores, A. (2011, Oct.). “Towards Intelligent Probiotics.” International Genetically Engineered Machine 2011 Americas Regional Jamboree: Indianapolis, IN.  Poster presentation.
  2. Brasseaux, C., Golynskiy, D., Guinn, M., & Sant, S. (2011) “Towards Intelligent Probiotics.” International Genetically Engineered Machine 2011 Americas Regional Jamboree: Indianapolis, Indiana. Oral presentation.
  3. Ehrhardt, K., Guinn, M., Quarton, T., and Bleris, L. (2012, Oct.). “Gene Circuits for Sensing Endogenous miRNAs.” Texas Analog Center of Excellence (TxACE) Symposium: Dallas, TX. Poster presentation
  4. Guinn, M., Li, Y., and Bleris, L.  (2013, Mar.). “Implementation and Optimization of a Synthetic Biological Decoder.” UT Metroplex Day: Dallas, TX. Poster presentation.
  5. Guinn, M., Li, Y., & Bleris, L. (2013). “A 2-input Decoder Circuit in Human Cells.” 5th International Workshop on Bio-Design Automation: London, United Kingdom, p 41-42. Abstract no. 27. Oral presentation.
  6. Guinn, M., Spinhirne, A., Cogan, T., & Blers, L. (2013, Sep.). “Reconfigurable Hybrid Sensors for In-situ Cancer Detection.” TECHCON 2013: Austin, TX. Poster presentation.
  7. Guinn, M., Spinhirne, A., Cogan, T., Bleris, L. (2013, Oct.). “Genetics Circuits for In-situ Cancer Detection.” Texas Analog Center of Excellence (TxACE) Symposium: Dallas, TX. Poster presentation.
  8. Guinn, M. & Bleris, L. (2013). “Reconfigurable Hybrid Sensors for In-situ Cancer Detection.” TECHCON 2013: Austin, Texas, p 34. Paper no. 2.8. Oral presentation.
  9. Guinn, M. & Bleris, L. (2014) “Biological 2-Input Decoder Circuit in Human Cells.” ALIFE 14 workshop: Computing with Biomolecules: From Network Motifs to Complex and Adaptive Systems: New York, New York. Oral presentation.
  10. Guinn, M. & Bleris, L. (2014). “Biological 2-Input Decoder Circuit in Human Cells.” 2014 AIChE Annual Meeting: Atlanta, Georgia. Oral presentation.
  11. Guinn, M., Balazsi, G. (2017, Oct.). “Optogenetic Tools for Controlling Genetic Circuits in Mammalian Cells.” Stony Brook MSTP Retreat: Stony Brook, NY. Poster presentation.
  12. Guinn, M., Balazsi, G. (2018, April.). “Optogenetic Tools for Characterizing Epithelial-Mesenchymal Transition.” Stony Brook MSTP Retreat: Stony Brook, NY. Poster presentation.
  13. Guinn, M., Balazsi, G. (2018, Aug.). “Optogenetic Feedback Systems in Synthetic Biology.” Stony Brook Biomedical Engineering Research Day: Stony Brook, NY. Poster presentation.
  14. Guinn, M., Balazsi, G. (2018, Oct.). “Optogenetic Gene-Circuit Tools for Precise Light-Controlled Gene Expression & Transcriptional Noise-Reduction in Mammalian Cells.” Stony Brook MSTP Retreat: Stony Brook, NY. Poster presentation.
  15. Guinn, M. & Balazsi, L. (2019, Mar.). “Synthetic Gene Circuits Controlling Precise Biological Pattern Formation in Multicellular-Mammalian Systems.” American Physical Society (APS) March Meeting 2019: Boston, Massachusetts. Oral presentation.
  16. Guinn, M., Balazsi, G. (2019, Apr.). “Precise Gene Expression Control of the Oncogene KRAS(G12V) Using Optogenetic Gene Circuits in Mammalian Cells.” Stony Brook MSTP Day: Stony Brook, NY. Poster presentation.
  17. Guinn, M. & Balazsi, L. (2019, Apr.). “Optogenetic Gene Circuits for Unraveling Potential Drug Targets through Precision Gene Expression Control” The Future of Principles-Based Drug Discovery: Mt Sinai-Laufer Center Retreat: Stony Brook NY, NY. Oral Presentation.
  18. Guinn, M. & Balazsi, L. (2019, Jun.). “Noise-Reducing Optogenetic Circuits in Mammalian Cells.” 2019 Synthetic Biology: Engineering, Evolution, & Design Conference (SEED 2019): New York, New York. Submitted. Rapid Fire Presentation & Poster Presentation.
  19. Guinn, M. & Balazsi, L. (2019, Jul.). “Mammalian Gene Expression Control & Noise Reduction using Optogenetic Negative Feedback Circuits” qBio 2019 Conference: San Francisco, California. Poster Spotlight Talk.
  20. Guinn, M. & Balazsi, L. (2019, Nov.). “Precision Gene Expression Control Utilizing Optogenetic Negative Feedback Circuits” Stony Brook Biomedical Engineering Seminar Talk: Stony Brook, NY. Oral Presentation.
  21. Guinn, M. & Balazsi, L. (2019, Nov.). “Spatiotemporal Control of Functional Gene Expression Utilizing Optogenetic Negative Feedback Circuits with Low Noise” Stony Brook Medical Scientist Training Program 2019 Retreat: Stony Brook, NY. Oral Presentation.

UNIVERSITY ARTICLES

  1. https://you.stonybrook.edu/mstp/2018/07/03/featured-alumni-dr-oladapo-yeku/
  2. https://you.stonybrook.edu/mstp/2018/12/07/featured-student-greg-kirschen-ms3/
  3. https://you.stonybrook.edu/mstp/2019/06/28/student-spotlight-alexander-jares-phd/
  4. https://you.stonybrook.edu/mstp/2020/01/13/its-an-honor-to-call-stony-brook-my-alma-mater/

IN THE NEWS

  1. https://news.stonybrook.edu/sb_medicine/tyler-guinn-wins-prestigious-department-of-defense-graduate-fellowship/