I joined the Orthopaedic Lab at Stony Brook University in my Spring semester of 2017, I started work alongside my PI, Dr. Yi-Xian Qin along with Wonsae Lee and Xiaofei Li, who trained me in the different skills needed to complete the wet lab work that would be conducted in lab. I began by shadowing Wonsae and Xiaofei and assisting them with their own projects before taking on my own project for the following summer and year.
I began working on a project with my lab partner, Connor Watson. For our project we began looking into the use of Low Intensity Pulsed Ultrasound (LIPUS) along with Polymer Microbubbles (MB) as a possible treatment method for bone degenrative diseases such as osteoporosis, as well as possible treatment methods for accelerating the repair of bone fractures and cartilage regeneration.
We worked over the summer of 2017, in which we accomplished a large amount of data collection on the use of LIPUS and MBs as a treatment in vivo. We measured the ALP Activity of cells under 4 conditions, a control, LIPUS only, MBs only, and LIPUS+MB. We were able to submit an abstract which was accepted to BMES 2017 where we would also present our data at the BMES Conference at Phoenix, Arizona.
We followed our work in the Spring of 2018, in which we completed more optimization of the given parameters and utilized a different assay in order to test the effectiveness of the treatment method. We were able to submit an abstract which was accepted to the BMES 2018 Conference at Atlanta, Georgia where we also presented a poster.
Graduate Researcher, Orthopaedic Bioengineering Research Laboratory
Stony Brook University, 215 Bioengineering Bldg.
Stony Brook, NY, 11794