Sexuality is a big part of a human life. Love, affection and sexual intimacy all play a role in healthy relationships. A number of disorders can affect the ability to have or enjoy sex in both men and women. The recent scientific research work on Human immunodeficiency virus type 1 (HIV-1) and Human cytomegalovirus (HCMV) has been published in an International peer-reviewed reputed Journal entitle “American Journal of Health Research”. HIV-1 is the main causative agent of acquired immune deficiency syndrome (AIDS). It is a worldwide pandemic disease, and the number of infected people around the world increase day by day. Human cytomegalovirus (HCMV) is a vernacular name of the human herpes virus – 5. It is a highly host-specific virus of the herpesviridae family rarely causes symptoms. The pregnant women and immune weakened persons are highly prone to acquire infection by HCMV virus. It spreads through various body fluids, such as blood, urine, saliva, semen, and breast milk. Immunomodulatory therapies are currently used against HIV-1 infections which include mycophenolate mofetil, cyclosporine, interleukin-2 (IL-2), and various vaccines. Although several treatment strategies are available against AIDS patients infected by HIV-1 such as antiretroviral agents and vaccination. But some difficulties are also present. Hence, there is a need of an alternative way which may be useful to determine the viral loads by either enhancing the application of existing agents or by means of some alternative strategy or developing new drugs. Mr. Mahendra Kumar Trivedi‘s own inherent unique biofield energy (The Trivedi Effect®) is an alternative approach which might be useful to improve these unfilled space associated with AIDS infected patients to some extent. Overall, the findings indicated that biofield treatment on the viral load in HIV-1 RNA infected stored plasma samples was significantly reduced by 65% as compared to control. Additionally, viral load of HCMV DNAaemia in infected stored plasma samples was also reduced by 80% in the biofield treated group as compared to control. The excellent findings from this experiment clearly message to the peoples in the Universe a tremendous impact of Trivedi Effect® on HIV and HCMV infected patients.