Innovation and Entrepreneurship Fellowship, 2019: Through this fellowship, I analyzed common single nucleotide polymorphisms that occurred in Alzheimer’s disease and Cerebral Small Vessel disease using genome-wide association studies and databases such as NCBI, ENSEMBL, and UNIPROT. Through this, I could discern one mutation in linkage disequilibrium with the APOE gene associated with both CSVD and AD pathology.
NSF-REU, 2020: In this project, I learned how to use FREESURFER and python to compare the brain volumes of grey and white matter in normal aging and Alzheimer’s diseased patients. I used python to code for a patient selection criterion that would be used to obtain a control and experimental data set. After obtaining a target set of patients, I used ADNI to obtain the brain images of these patients and parcellated them with FREESURFER. With these parcellations, I obtained the control and experimental set’s grey and white matter volumes. Then I created a regression algorithm that would relate age to brain volume changes.
Biomedical Engineering Design Award, 2022: During the final year of my undergraduate career, my teammates and I developed a fatigue monitoring system for navy submarine operators. The fatigue monitoring system consisted of a Garmin watch and a custom-made respirator strap. The algorithm is a support vector regression algorithm, which can learn an individual’s baseline fatigue levels and indicate when an individual’s fatigue levels are beyond the baseline.