Welcome to the Yang Research Lab!
Despite remarkable progress in cancer treatment over the past decade, cancer metastasis remains responsible for about 90% of cancer deaths. Hence, there is an urgent imperative to deepen our understanding of metastasis and proactively prevent the development of life-threating macrometastases. To address this critical challenge, the Yang lab focuses on harnessing the power of multi-level proteomics technologies, such as global proteomics, phosphoproteomics, palmitoyl-proteomics, interactome profiling, thermal proteome profiling, and targeted proteomics, to delineate the molecular mechanisms of cancer metastasis. The ultimate goal is to identify promising drug targets and reliable biomarkers, enabling precision treatment of patients facing a high risk of metastatic progression.