My current research is about In-vivo brain optical imaging (especially in mice’s brains). We use a multimodal imaging platform which developed in our lab to permit the simultaneous images of cellular activity (neuron and/or astrocyte) and hemodynamic responses (blood flow and tissue oxygen) in the different brain cortex (such as PFC, SSC) induced by different stimulation (electricity and/or drugs).

(X. Gu, W. Chen, N. D. Volkow, A. P. Koretsky, C. Du, and Y. Pan, ‘Synchronized Astrocytic Ca(2+) Responses in Neurovascular Coupling During Somatosensory Stimulation and for the Resting State’, Cell Rep, 23 (2018), 3878-90.)