Research

Current Research
Dr. Richard Clark, M.D., SUNY Stony Brook University
Graduate Research Assistant
Aug 2017-Current
The Clark Lab is interested in the effect of a fibronectin-derived peptide, P12, has on burn wounds. P12 was found through Western blots to up-regulate proteins needed for wound healing. Previous porcine models have also shown increased healing speed and reduced scarring with P12. The current porcine trials are interested in how the delivery of the peptide (intravenous versus topical) and time between burn and P12 application (24 versus 48 hours) affects the peptides potency. As a supplement to these trials, I have been taking infrared (IR) images of the burns and their progression with the aim to develop a system that can predict burn depth and burn zones based on temperature of the wound site.
Associated Skills:
Animal testing, Western blot, IR image processing

Sample IR image of a burn with biopsy 7 days after initial burn.

Past Research
Dr. Wei Yin, Ph.D., SUNY Stony Brook University
Undergraduate Research Assistant
Aug 2014 – May 2015
I treated platelets with factors to various shear stresses to induce thrombin generation. Then, those cells are treated with fluorescent antibodies in order to quantify thrombin generation through P-selectin activation using flow cytometry. The data has been published as “Flow Regulates Thrombin Generation Kinetics” in FASEB.
Associated Skills:
ELISA, flow cytometry, hemolysis assay, aggregation assay

Dr. Stefan Judex, Ph.D., SUNY Stony Brook University
Undergraduate Research Assistant
Aug 2013 – May 2014
I cultured animal mesenchymal stem cells and human osteoblast cells which were then presented with mechanical stimuli of varying accelerations over several days. The cell proliferation population was recorded and the proliferation rate was found. The tested cells were then parachuted onto osteoblast cells to see if the stimuli significantly increased stem cell differentiation into osteoblast cells.
Associated Skills:
Cell culture, proliferation assay