PUBLICATIONS

Peer-Reviewed Journal Papers

  1. Qin, YX., McLeod, K.J., Guilak, F., Chiang, F-P and Rubin, C.T. (1996): Correlation of Bony Ingrowth to the Distribution of Stress and Strain Parameters Surrounding a Porous‑Coated Implant.  Ortho. Res. 14:862‑870.
  2. Rubin, C.T., Gross, T., Qin, YX., Fritton, S., Guilak, F., and McLeod, K.J. (1996): Differentiation of the Bone Tissue Remodeling Response to Axial and Torsional Loading in the Turkey Ulna. J. Bone Joint Surg. 78‑A:1523‑1533.
  3. Qin, YX., Zhu, L., Young, C. and Hsu, W. (1988): PEF‑1 Type Occlusal Force Meter and Its Clinical Applications. Chinese J. Stomatology, 8:18‑22.
  4. Qin, YX., Wang, W., and Shao, Q. (1987): The Method of Ultrasonic Convergency for the Blood Flow Measurement with Doppler Ultrasound in the Small Vessel on Oral and Maxillofacial Regions. Chinese J. Biomedic. Eng., 6:132‑136.
  5. Qin, Y., McLeod, K., Otter, M., & Rubin, C. (1997): Intracortical Pore Fluid Pressure and Gradients Generated by Dynamic Loading and Their Potential Role in Bone Adaptation. Annals of Biomed. Eng., 25:449-460
  6. Fritton, J.C., Rubin, C.T., Qin, YX, and McLeod, K.J. (1997): Vibration in the Skeleton: I. Development of a Resonance‑Based Whole Body Vibration Device. Annals of Biomedical Engineering 25:6-12.
  7. Qin, YX., Rubin, C.T., & McLeod, K.J. (1998): Non‑linear Dependence of Loading Intensity and Cycle Number in the Maintenance of Bone Mass and Morphology. J. Orthop. Res. 16:482-489.
  8. McLeod, K.J., Rubin, C.T., Otter, M.W. and Qin, YX. (1998): Skeletal Cell Stresses and Bone Adaptation. Am. J. Med. Sci., 316:176-183.
  9. Otter, M.W., Qin, YX., Rubin, C.T. and McLeod, K.J. (1999): Does Bone Perfusion/Reperfusion Initiate Bone Remodeling and the Stress Fracture Syndrome? Medical Hypotheses,53(5):363-368.
  10. Khalsa, P.S., Zhang, C., & Qin, YX. (2000): Encoding of Location and Intensity of Noxious Indentation into Rat Skin by Spatial Populations of Cutaneous, Mechano-Nociceptors. J. Neurophysiology, 83:3049-3061.
  11. Lin, W., Qin, YX., and Rubin, C.T. (2001): Ultrasonic Wave Propagation in Trabecular Bone Predicted by the Stratified Model. Annals Biomed Eng, 29(9): 781-790.
  12. Rubin, C. T., Sommerfeldt, D. W., Judex, S. and Qin, YX. (2001): Inhibition of Osteopenia by Low Magnitude, High Frequency Mechanical Stimuli. Drug Discovery Today, 6:16:848-858.
  13. Demes, B., Qin, YX., Stern, J. T. Jr., Larson, S. G., Rubin, C.T. (2001): Patterns of strain in the macaque tibia during functional activity. Am J Physcial Anthropology, 116:257-265.
  14. Qin, YX., Lin, W., and Rubin, C.T. (2002): The Pathway of Bone Fluid Flow as Defined by In Vivo Intramedullary Pressure and Streaming Potential Measurements, Annals Biomed Eng, 30:693-702.
  15. Rubin, C. T., Turner, S., Muller, R., Mittra, E., McLeod, K., Lin, W., and Qin, YX. (2002): Quantity and Quality of Trabecular Bone in the Femur are Enhanced by a Strongly Anabolic, Noninvasive Mechanical Intervention. J Bone Min Res, 17(2): 349-357. PMID: 11495758
  16. Beck, B., Qin, YX., McLeod, K.J. and Otter, M (2002): On the relationship between streaming potential and strain in an in vivo bone preparation. Calcif Tiss Intl, 71(4):335-343.
  17. Judex, S., Boyd, S., Qin, YX, Miller, L., Müller, R., Rubin, C. (2003)  Combining High-Resolution MicroCT with Material Composition to Define the Quality of Bone Tissue.  Current Osteoporosis Reports.  1:11-19
  18. Qin, YX., Kaplan, T., Saldanah, A. and Rubin, C.T. (2003): Fluid Pressure Gradients, Arising from Oscillations in Intramedullary Pressure, is Correlated with the Formation of Bone and Inhibition of Intracortical Porosity. J Biomech, Oct;36(10):1427-37.
  19. Judex, S., Boyd. S., Qin, YX., Turner, S., Ye, K., Müller, R., Rubin, C. (2003): Adaptation of trabecular bone to low magnitude vibrations result in increased stiffness and more uniform stress and strain under load. Annals Biomed Eng, 31(1), 12-20.
  20. Xia, Y., Lin, W. and Qin, YX. (2005): The Influence Of Cortical End-Plate On Broadband Ultrasound Attenuation Measurements At The Human Calcaneus Using Scanning Confocal Ultrasound. J Acoustic Soc of Am, 118 (3):1801-1807. PMID: 16240838
  21. Mittra, E., Rubin, C. and Qin, YX. (2005): Interrelationship of trabecular mechanical and microstructural properties in sheep trabecular bone. J Biomech, 38(6):1229-37.
  22. Busa, B., Miller, L., Qin, YX., Rubin, C., Judex, S. (2005): Rapid Establishment of Chemical and Mechanical Properties during Lamellar Bone Formation. Cal Tis Intl’, Dec; 77(6):386-94.
  23. Mittra, E., Akella, S. and Qin, YX. (2006): The effects of embedding material, loading rate and magnitude, and penetration depth in nanoindentation of trabecular bone. J Biomed Mat Res, Part-A, Oct;79(1):86-93.
  24. Lin, W. Mittra, E. and Qin, YX. (2006): Determination of ultrasound phase velocity in trabecular bone using time dependent phase tracking technique. J Biomech Eng, Feb., 128(1):24-29.
  25. Qin, YX., Lam, H.Y., Orzechowski, L. (2006): Anabolic Fluid Flow Stimulation is responsible for Bone Formation as a Manner of Specific Frequency and Magnitude. Int’l Proceeding of 5th World Congress of Biomech, Ed. By D. Liepsch. Medimond S.r.l., ISBN 88-7587-270-8, pg: 45-49.
  26. Mankani, M.H., Kuznetsov, S.A., Shannon, B., Nalla, R.K., Ritchie, R.O., Qin, Y., Robey, P.G. (2006): Canine Cranial Reconstruction Using Autologous Bone Marrow Stromal Cells. Am J Pathology, 168, No. 2, Feb.
  27. Rubin, C. T., Judex, S., Qin, YX. (2006): Low-level mechanical signals and their potential as a non-pharmacological intervention for osteoporosis. Age and Ageing, 35-S2: ii26–ii30.
  28. Xia, Y., Lin, W. and Qin, YX. (2007): Bone Surface Topology Mapping and its Role in Trabecular Bone Quality Assessment using Scanning Confocal Ultrasound. Osteoporosis Intl, Jul;18(7):905-13. PMID: 17361323
  29. Ni, Q., De Los Santos, A, Lam, H., Qin, YX. (2007): Assessment of Simulated and Functional Disuse on Cortical Bone by Nuclear Magnetic Resonance. Adv in Space Res, 40:1703-10.
  30. Mittra, E., Rubin, C., Gruber, B. and Qin, YX. (2008): Evaluation of trabecular mechanical and microstructural properties in human calcaneal bone of advanced age using mechanical testing, mCT, and DXA. J Biomech, 41:368-375.
  31. Qin, YX., Xia, Y., Lin, W., Mittra, E., Rubin, C., Gruber, B. (2008): Noninvasive Ultrasound Imaging for Bone Quality Assessment using Scanning Confocal Acoustic Diagnosis, mCT, DXA Measurements, and Mechanical Testing. LNCS, ISSN:0302-9743 (p)/1611-3349 (online). Dec, 4901:216-233.
  32. Ozcivici E, Ferreri S, Qin YX, Judex S (2008): Determination of bone’s mechanical matrix properties by nanoindentation. Osteoporosis – Methods Mol Biol. 455:323-34
  33. Meng Y., Qin YX., DiMasi E., Ba X., Rafailovich M., Pernodet N. (2008): Biomineralization of a Self-Assembled Extracellular Matrix for Bone Tissue Engineering. Tis Eng, Part A, 15(2):355-366.
  34. Lam H., Qin YX. (2008): The effects of frequency-dependent dynamic muscle stimulation on inhibition of trabecular bone loss in a disuse model. Bone, 43(6):1093-100.
  35. Qin YX., Lam H. (2009): Intramedullary Pressure and Matrix Strain Induced by Oscillatory Skeletal Muscle Stimulation and its Potential in Adaptation. J Biomech, 42(2):140-145. PMID: 19081096.
  36. Lin, W., Xia, Y. and Qin, YX. (2009): Characterization of the trabecular bone structure using frequency modulated ultrasound pulse. J Acoust Soc Am. Jun;125(6):4071-7
  37. Zhang Z, Yan Y, Lim Y, Tang D, Xie R, Chen A, Tai T, Harris SE, Xing L, Qin YX, Chen D (2009): BMP-2 Modulates β-Catenin Signaling through Stimulation of Lrp5 Expression and Inhibition of β-TrCP Expression in Osteoblasts. J Cellular Biochem, Nov 1;108(4):896-905.
  38. Ozcivici E., Luu YK, Adler B, Qin YX, Rubin J, Judex S, Rubin CT (2010): Mechanical Signals as Anabolic Agents in Bone. Nat Rev Rheum. Jan;6(1):50-9.
  39. Lam H., Brink, P., Qin YX. (2010): Skeletal Nutrient Vascular Adaptation Induced by External Oscillatory Intramedullary Fluid Pressure Intervention. J Ortho Surg Res, 5(1):18. PMID: 20222973.
  40. Ba X., Rafailovich M., Meng Y., Pernodet N., Wirick S., Füredi-Milhofer H., Qin YX, DiMasi E. (2010): Complementary effects of multi-protein components on biomineralization in vitro. J Struct Biology. 170(1):83-92.41.      
  41. Qin YX., Lam H. Ferreri S, Rubin C. (2010): Dynamic Skeletal Muscle Stimulation and its Potential in Bone Adaptation. J Musculoskeletal and Neuronal Interactions. March, 10(1):12-24. PMID: 20190376.
  42. Lam H., Hu M., Qin YX. (2011): Alteration of Contraction-to-Rest Ratio to Optimize Trabecular Bone Adaptation Induced by Dynamic Muscle Stimulation. Bone, Feb;48(2):399-405, PMID: 20850577.
  43. Qin, YX. (2010): Challenges to the Musculoskeleton during a Journey to Mars:Assessment and Counter Measures. J Cosmology, 12:3778-3780.
  44. Muir J., Judex S., Qin YX., Rubin C. (2011): Postural Instability Caused by Extended Bed Rest Is Alleviated by Brief Daily Exposure to Low Magnitude Mechanical Signals. Gait & Posture, 33:429-435.
  45. Uddin S.M.Z., Cheng J., Lin W., Qin YX. (2011): Low-Intensity Amplitude Modulated Ultrasound Increases Osteoblastic Mineralization. Cell Molecular Bioeng, 4:81-90.
  46. 46.      Cheng, J., Lu, J., Lin, W., and Qin, YX. (2011): A new algorithm for spatial impulse response of rectangular planar transducers. Ultrasonics, Feb;51(2):229-37. Epub 2010 Sep 4. PMID: 2086354347.
  47. Ferreri, S., Talish, R., Trandafir, T., Qin, YX. (2011): Mitigation of bone loss with ultrasound induced dynamic mechanical signals in an OVX induced rat model of osteopenia. BONE, May 1; 48(5):1095-102, PMID: 21241838.48.
  48. Cheng J, Lu JY, Lin W, Qin YX (2011): A new algorithm for spatial impulse response of rectangular planar transducers. Ultrasonics, Feb;51(2):229-37.49.
  49. Cheng J, Lin W, Qin YX (2011): Extension of the distributed point source method for ultrasonic field modeling. Ultrasonics, 5:571-580.50.
  50. Serra-Hsu F, Cheng J, Lynch T, Qin YX (2011): Evaluation of a pulsed phase-locked loop system for noninvasive tracking of bone deformation under loading with finite element and strain analysis. Physiol Meas. Aug; 32(8):1301-12. PMID: 21765205.
  51. Cheng J, Serra-Hsu F, Tian Y, Lin W, Qin YX (2011): Effects of phase cancellation and receiver aperture size on broadband ultrasonic attenuation for trabecular bone in vitro. Ultrasound Med Biol, Dec;37(12):2116-25. Epub 2011 Oct 26. PMID: 22033134.
  52. Qin YX., Zhang S., Ferreri S, Cheng J. (2012): Therapeutic ultrasound on bone cellular and in vivo adaptation. J Acoust Soc Am, 131(4):3458.
  53. Lin L, Cheng J, Lin W, Qin YX (2012): Prediction of Trabecular Bone Principal Structural Orientation using Quantitative Ultrasound Scanning. J Biomech, 45(10):1790-5. PMID:22560370.54.
  54. Zhang S, Cheng J, Qin YX (2012): Mechanobiological modulation of cytoskeleton and calcium influx in osteoblastic cells by short-term focused acoustic radiation force. PLoS ONE, 7(6):e38343, PMID: 22701628.55.
  55. Lin, W., Serra-Hsu, F., Cheng, J., and Qin, YX. (2012): Frequency Specific Ultrasound Attenuation Is Sensitive to Trabecular Bone Structure. Ultrasound Med Biol, 38(12):2198-2207. PMID: 22975035.56.
  56. Hu, M., Cheng, J., Qin YX. (2012): Dynamic hydraulic flow stimulation on mitigation of trabecular bone loss in a rat functional disuse model. Bone, Jul 20, 51(4):819-25, PMID: 22820398.57.
  57. Li Z, Zuo L, Luhrs G, Lin L and Qin YX (2013): Electromagnetic Energy-Harvesting Shock Absorbers: Design, Modelling and Road Tests. IEEE Transaction on Vehicular Technology. 62(3):1065-74. http://ieeexplore.ieee.org/xpls/abs_all.jsp?arnumber=6399623.58.
  58. Qin, YX., Lin, W., Mittra, E., Xia, Y., Cheng, J., Judex, S., Rubin, C., Müller, R. (2013): Prediction of trabecular bone qualitative properties using scanning quantitative ultrasound. Acta Astronautics, 92(1):79-88. PMID: 23976803.59.
  59. Uddin, SZ., Hardjiargyou, M., Cheng, J., Zhang, S., Hu, M., and Qin, YX. (2013): Reversal of the Detrimental Effects of Simulated Microgravity on Human Osteoblasts by Modified Low Intensity Pulsed Ultrasound. Ultrasound Med Biol, 39(5):804-12, PMID: 23453382. 60.
  60. Hu, M., Yeh, R., Lien, M., Teeratananon, M., Agarwal, K., Qin YX. (2013): Dynamic Fluid Flow Mechanical Stimulation Modulates Bone Marrow Mesenchymal Stem Cells. Bone Research, 1(1):94-104.61.
  61. Lalwani, G., Henslee, A., Farshid, B., Lin, L., Kasper, F., Qin, YX., Mikos, A., Sitharaman, B. (2013): Two-Dimensional Nanostructure- Reinforced Biodegradable Polymeric Nanocomposites for Bone Tissue Engineering. Biomacromolecules, bm-2012-01995s. 14(3):900-9. PMID: 23405887. 62.
  62. Lalwani, G., Henslee, A., Farshid, B., Lin, L., Kasper, F., Qin, YX., Mikos, A., Sitharaman, B. (2013): Tungsten Disulfide Nanotubes Reinforced Biodegradable Polymers for Bone Tissue Engineering. Acta Biomaterialia 9(9):8365-73. PMID: 23727293.63.
  63. Klein GL, Xie Y, Qin YX, Lin L, Hu M, Enkhbaatar P, Bonewald LF (2013): Preliminary Evidence of Acute Bone Resorption in a Sheep Model of Acute Burn Injury: An Observational Study. Journal of Bone and Mineral Metabolism, Jun 20. PMID: 23784552.64.
  64. Ni Q, Dixon H, Gutierrez G, Bi L, Qin, YX. (2013): Characterization of Synthesized Nano-encapsulated Drug for Bone Loss on Hind Limb Suspension Rat Model by NMR and Micro-CT. Adv in Bioscience and Bioengineering. 1(1):1-7, doi: 10.11648/j.abb.20130101.11.65.
  65. Hu M, Serra-Hsu F, Bethel N, Lin L, Ferreri S, Cheng J, Qin YX. (2013): Dynamic Hydraulic Fluid Stimulations Regulated Intramedullary Pressure. BONE, 57(1): 137-41. PMID: 23895997.66.
  66. Uddin, SZ., and Qin, YX. (2013): Enhancement of Osteogenic Differentiation and Proliferation in Human Mesenchymal Stem Cells by a Modified Low Intensity Ultrasound Stimulation under Simulated Microgravity. PLoS ONE, Sep 12:8(9): e73914. PMID: 24069248.67.
  67. Lin L, Lin W, Qin YX. (2013): Integrated transmission-reflection quantitative ultrasound noninvasive prediction of trabecular bone principal structural orientation validated with mechanical testing. J Acoust Soc Am, 134(5): 4121. PMID: 24181472.68.
  68. Rubin CT, Seeherman H, Qin YX, Gross TS (2013): The mechanical consequences of load bearing in the equine third metacarpal across speed and gait: the nonuniform distributions of normal strain, shear strain, and strain energy density. FASEB J. 27(5):1887-94. PMID: 23355269.69.
  69. Xu K, Ta D, He R, Qin YX, Wang W (2014): Axial transmission method for long bone fracture evaluation by ultraonic guided waves: Simulation, phantom and in-vitro experiment. Ultrasound Med Biol, 40(4):817-27. PMID: 24433749.70.
  70. Lin L, Oon HY, Lin W, Qin YX. (2014): Principal trabecular structural orientation predicted by quantitative ultrasound is strongly correlated with μFEA determined anisotropic apparent stiffness. Biomech Model Mechanobiol, Jan. 14, PMID: 24419558.71.
  71. Hu M, Qin YX (2014): Dynamic Fluid Stimulation on Cortical Bone and Alterations of the Gene Expressions of Osteogenic Growth Factors and Transcription Factors in a Rat Functional Disuse Model. Archives of Biochem and Biophysics, 545:154-61. PMID: 24486201.72.
  72. Wu L, Lin L, Qin YX (2014): Enhancement of Cell Ingrowth, Proliferation and Early Differentiation in a 3-D SiC Scaffold using Low-Intensity Pulsed Ultrasound. Tissue Eng Part A. Jun 16, PMID: 24935158.73.
  73. Hu M, Cheng J, Bethel N, Serra-Hsu F, Ferreri S, Lin L, Qin YX (2014): Interrelation between External Oscillaroty Muscle Coupling Amplitude and in vivo Intramedullary Pressure Related Bone Adaptation. BONE, Jun 17;66C:178-181. PMID: 24947450.74.
  74. Qin YX, Hu M (2014): Mechanotransduction in Musculoskeletal Tissue Regeneration – Effects of Fluid Flow, Loading, and Cellular-Molecular Pathways. BioMed Res International, (Epub 2014 Aug 18). PMID: 2521529575.
  75. Pei GX, Qin YX, Hutmacher DW, Zhang ZY (2014): Bone Tissue Engineering: Cell Motility, Vascularization, Micro-Nano Scaffolding, and Remodeling. Editorial, BioMed Res International, (Epub 2014 Aug 19). PMID: 2521070876.
  76. Wu J, Liu G, Qin YX, Meng Y (2014): Effect of low-intensity pulsed ultrasound on biocompatibility and cellular uptake of chitosan-TPP nanoparticles. Biointerphases, 9(3):031016. PMID: 25280857.77.
  77. Lin L, Ambike E, Sahul R., Qin YX. (2014): Super wideband quantitative ultrasound imaging for trabecular bone with novel wideband single crystal transducer frequency sweep measurement. J Acoust Soc Am, 135(4): 2372. PMID: 2523588178.
  78. Zhou Y, Mohan A, Moore DC, Lin L, Zhou FL, Cao J, Wu Q, Qin YX, Reginato AM, Ehrlich MG, Yang W (2015): SHP2 regulates osteoclastogenesis by promoting preosteoclast fusion. FASEB J. 2015 Jan 1, PMID: 25593124.79.
  79. Li XF, Cai XR, Fan F, Niu HJ, Li SY, Li DY, Fan YB, Qin YX. (2015): Observation of sGAG content of human hip joint cartilage in different old age groups based on EPIC micro-CT. Connective Tis Res, Apr;56(2):99-105, PMID: 25602512.80.
  80. Uddin, SZ., and Qin, YX. (2015): Dynamic Acoustic Radiation Force Retains Bone Structural and Mechanical Integrity in a Functional Disuse Osteopenia Model. Bone, Jun;75:8-17, PMID: 25661670.81.
  81. Lin L, Lin W, Qin YX. (2015): Enhanced correlation between quantitative ultrasound and structural and mechanical properties of bone using combined transmission-reflection measurement. J Acoust Soc Am, Mar;137(3):1144. PMID: 25786930.82.
  82. Hu M, Tian GW, Gibbons DE, Qin YX (2015): Dynamic Fluid Flow Induced Mechanobiological Modulation of In Situ Osteocyte Calcium Oscillations. Arch Biochem Biophys, Jun 1;579:55-61. PMID: 26045248.83.
  83. Lalwani, G, Gopalan A, D’Agati M, Srinivas Sankaran J, Judex S, Qin YX, Sitharaman, B (2015): Porous three-dimensional carbon nanotube scaffolds for tissue engineering. J Biomed Mater Res A. Mar 18. doi: 10.1002/jbm.a.35449. PMID: 25788440.84.
  84. Patel SC, Lalwani G, Grover K, Qin YX, Sitharaman, B (2015): Fabrication and cytocompatibility of in situ crosslinked carbon nanomaterial films. Sci Rep. 2015 May 28;5:10261. doi: 10.1038/srep10261. PMID: 26018775.85.
  85. Grover K, Lin L, Hu M, Muir J, Qin YX. (2016): Spatial distribution and remodeling of elastic modulus of bone in micro-regime as prediction of early stage osteoporosis. J Biomech, 49(2):161-6. PMID: 26705110.86.
  86. Zhang D, Hu M, Chu T, Lin L, Wang J, Li X, Ke HZ, Qin YX (2016): Sclerostin antibody prevented progressive bone loss in combined ovariectomized and concurrent functional disuse. BONE, 87:161-8. PMID: 26868528.87.
  87. Zhang D, Hu M, Chu T, Lin L, Wang J, Li X, Ke HZ, Qin YX (2016): Erratum to Sclerostin antibody prevented progressive bone loss in combined ovariectomized and concurrent functional disuse. BONE, 89:86. PMID: 27262889.88.
  88. Uddin SZ, Richbourgh B, Li YS, Komastu D, Qin YX, and Liu C (2016): Chondro-Protective Effects of Low Intensity Pulsed Ultrasound. Osteoarthritis and Cartilage, Nov;24(11):1989-1998. PMID: 27364595.89.
  89. Vojdani S, Fernandez L, Jiao J, Enders T, Ortiz S, Lin L, Qin YX, Komatsu DE, Penna J, Ruotolo CJ (2016): Novel Spiked-Washer Repair Is Biomechanically Superior To Suture And Bone Tunnels for Arcuate Fracture Repair. J Orthop Trauma. PMID: 27984448.90.
  90. Patel S, Owais A, Zhang D, Grover K, Qin YX, Sitharaman B. (2016): Layer-by-Layer, Ultrasonic Spray Assembled 2D and 3D Chemically Crosslinked Carbon Nanotubes and Graphene. J Materials Res. (in press).91.
  91. Hu M, Lam H, Yeh R, Teeratananon M, Qin YX (2017): Comparison of Morphological Changes of Muscle Fibers in Response to Dynamic Electrical Muscle Contraction and Dynamic Hydraulic Stimulation in a Rat Hindlimb Disuse Model. Physiological Res. (Epub). PMID: 28248540.92.
  92. Meng Y., Faillace ME, Dorst K, Palmaccio SJ, Miller L, Qin YX (2017): In situ examination of osteoblast biomineralization on sulfonated polystyrene-modified substrates using Fourier transform infrared microspectroscopy. Biointerphases. (Epub). PMID: 28693327.93.
  93. Yuan M, Wang Y, Qin YX (2017): SPIO-Au core-shell nanoparticles for promoting osteogenic differentiation of MC3T3-E1 cells: concentration-dependence study. J Biomed Materials Res: Part A. (Epub). PMID: 2886970794.
  94. Gadomski B, McGilvray KC, Easley JT, Palmer RH, Qin YX, Puttlitz C (2017): An Investigation of Shock Wave Therapy and Low-Intensity Pulsed Ultrasound on Fracture Healing Under Reduced Loading Conditions in an Ovine Model. J Orthop Res. (Epub). PMID: 28762588.95.
  95. Yuan M, Wang Y, Longtin J, Hwang D, Qin YX (2017): Tunable SPIO-Au core-shell nanoparticles with high photothermal efficiency: thermocouple-tip-exposing temperature assessment and biocompatibility study. Journal of Biomedical Materials Research: Part A. 105(12):3350-3359. PMID: 2886970796.
  96. Zhang ZK, Guo X, Lao J, Qin YX (2017): Effect of capsaicin-sensitive sensory neurons on bone architecture and mechanical properties in the rat hindlimb suspension model. J Orthop Translat. July 2017. PMID: 2966275697.
  97. Zhu D, Su Y, Zheng Y, Fu B, Tang L, Qin YX (2018): Zinc regulates vascular endothelial activities through zinc-sensing receptor ZnR/GPR39. Am J Physiology – Cell Physiology. 1;314(4):C404-C414. PMID: 2935141798.
  98. Moonga S, Qin YX (2018): MC3T3 Infiltration and Proliferation in Bovine Trabecular Scaffold Regulated by Dynamic Flow Bioreactor and augmented by Low-Intensity Pulsed Ultrasound. J Orthop Translation, 2018 Mar 15;14:16-22, PMID: 30035029.99.
  99. Yuan M, Wang Y, Qin YX (2018): Promoting neuroregeneration by applying dynamic magnetic fields to a novel nanomedicine: superparamagnetic iron oxide (SPIO)-gold nanoparticles bounded with nerve growth factor (NGF. Nanomedicine: Nanotechnology, Biology, and Medicine. 5;14(4):1337-1347. PMID: 29627520100.
  100. Chen XJ, Yang F, Chen ZQ, He MC, Hong GJ, Huang JY, Zhou YC, Qin YX, Wei QS, He W (2018): Association of reduced sclerostin expression with collapse process in patients with osteonecrosis of the femoral head. Int Orthop. Jul;42(7):1675-1682, PMID: 29785591.
  101. Richardson MW, Tsouris ND, Hassan CR, Elbayar JH, Qin YX, Komatsu D, Rizzi AV, Paci JM (2019): A Biomechanical Comparison of Alternative Graft Preparations for All-Inside Anterior Cruciate Ligament Reconstruction. Arthroscopy. May;35(5):1547-1554. PMID: 30987907
  102. Su Y, Cockerill I, Wang Y, Qin YX, Chang L, Zheng Y, Zhu D (2018): Zinc-Based Biomaterials for Regeneration and THerapy. Trends in Biotechnology, TIBTEC 1720 (E-pub)103.
  103. Zhang D, Miranda M, Li X, Han J, Sun Y, Rojas N, He S, Hu M, Lin L, Li X, Ke HZ, and Qin YX (2019): Retention of osteocytic micromorphology by sclerostin antibody in a concurrent ovariectomy and functional disuse model. Annals NY Academy Sci, Special Issue: Musculoskeletal Repair and Regeneration. NYAS 13991 (E-pub). Apr;1442(1):91-103, PMID: 30644553104.
  104. Li X, Sun Y, Zhou Z, Zhang D, Jiao J, Hu M, Hassan CR, and Qin YX (2019): Mitigation of articular cartilage degeneration and subchondral bone sclerosis in osteoarthritis progression using low-intensity ultrasound stimulation. Ultrasound Med & Biol, https://doi.org/10.1016/j.ultrasmedbio. 2019 Feb 20;11(7):6809-6819. PMID: 30693753105.
  105. Qin YX, Xia Y, Muir J, Lin W, Rubin CT (2019): Quantitative ultrasound imaging monitoring progressive disuse osteopenia and mechanical stimulation mitigation in calcaneus region through a 90-day bedrest human study. J Orthop Translation, https://www.sciencedirect.com/science/article/pii/S2214031X18300275. 2018 Dec 24;18:48-58. PMID: 31508307106.
  106. Liu J, Li X, Zhang D, Jiao J, Wu L, Hao F, and Qin YX (2018): Acceleration of Bone Defect Healing and Regeneration by Low-Intensity Ultrasound Radiation Force in a Rat Tibial Model. Ultrasound Med & Biol, Dec;44(12):2646-2654. PMID: 30286949107.
  107. Zhu D, Cockerill I. Su Y, Zhang Z, Fu J, Lee K-W, Ma J, Okpokwasili C, Tang L, Zheng Y, Qin YX, Wang Y (2019): Mechanical Strength, Biodegradation, and In Vitro and In Vivo Biocompatibility of Zn Biomaterials. ACS Applied Mat & Interfaces. 2019 Feb 20;11(7):6809-6819. PMID: 30693753108.
  108. Zhu D, Cockerill I. Su Y, Zhang Z, Fu J, Lee K-W, Ma J, Okpokwasili C, Tang L, Zheng Y, Qin YX (2019): Interfacial zinc phosphate is the key controlling biocompatibility of metallic zinc implants. Adv Sci. (accepted).109.
  109. He M, Gong SD, Chen XJ, Yang F, Pang FX, Chen ZQ, Huang JY, Zhou YC, Qin YX, He W, Wei QS (2018): Plasma C-terminal cross-linking telopeptide of type II collagen as a biomarker in advanced stages of femoral head osteonecrosis. Biomed Pharmacother. 111:1213-1220. PMID: 30841434.110.
  110. Su Y, Chang L, Cockerill I, Zheng Y, Tang L, Qin YX, Zhu D (2019): Biofunctionalization of metallic implants by calcium phosphate coatings. Bioact Mater. 2019 May 20;4:196-206. Doi: 10.1016/j.bioactmat.2019.05.001. PMID: 31193406111.
  111. Gong SD, Chen XJ, Chen ZQ, He XM, Pang FX, Huang JY, Zhou YC, Qin YX, Liu SJ, Wei QS (2019): Elevated plasma cartilage oligomeric matrix protein (COMP) level are associated with the progression of non-traumatic osteonecrosis of femoral head. Clin Chim Acta. Mar;490:214-221, PMID: 30217750112.
  112. Su Y, Wang K, Gao J, Yang Y, Qin YX, Zheng Y, Zhu D (2019): Enhanced Cytocompatibility and Antibacterial Property of Zinc Phosphate Coating on Biodegradable Zinc Materials. ACTA Biomaterials. Oct 15;98:174-185, PMID: 30930304113.
  113. Grover K, Hu M, Lin L, Muir J, Qin YX. (2019): Functional disuse initiates medullary endosteal micro-architectural impairment in cortical bone characterized by nanoindentation. J Bone and Mineral Metabolism. 2019 Nov;37(6):1048-1057, PMID: 31292723
  114. Wang Y, Xue Y, Wang J, Zhu Y, Zhu Y, Zhang X, Liao J, Li X, Wu X, Qin YX, Chen W (2019): A composite hydrogel with high mechanical strength, fluorescence, and degradable behavior for bone tissue engineering. Polymers. 2019 Jul 1;11(7):1112. doi: 10.3390/polym11071112. PMID: 31266178
  115. Yuan M, Wang Y, Qin YX (2019): Engineered nanomedicine for neuroregeneration: Light emitting diode-mediated superparamagnetic iron oxide-gold core-shell nanoparticles functionalized by nerve growth factor. Nanomedicine: Nanotech, Biol, & Med. Oct;21:102052. PMID: 31349088116.
  116. Su Y, Yang H, Gao J, Qin YX, Zheng Y, Zhu D (2019): Interfacial zinc phosphate is the key controlling biocompatibility of metallic zinc implants. Adv Science. May 17;6(14):1900112. PMID: 31380203117.
  117. Sun S, Sun L, Kang Y, Tang L, Qin YX, Ta D (2019): Therapeutic effects of low-intensity pulsed ultrasound with different intensities on osteoporosis in ovariectomized rats – intensity dependent study. Ultrasound Med & Biol. 2020 Jan;46(1):108-121. PMID: 31587953
  118. Su Y, Cockerill I, Wang Y, Qin YX, Chang L, Zheng Y, Zhu D (2019): Zinc-based biomaterials for regeneration and therapy. Trends Biotechnol. 2019 Apr;37(4):428-441, PMID: 30470548
  119. Gurevich M, Hassan CR, Denney BS, Qin YX, Penna J, Komatsu DE (2019): Effect of 1.5 mm biter-width meniscectomy on cadaveric knee pressures. J Orthop Surg Res (in review).120.
  120. Hassan CR, Qin YX, Komatsu D, Uddin SZ (2019): Utilization of Finite Element Analysis for Articular Cartilage Tissue Engineering. Materials. Oct 12;12(20), PMID: 31614845
  121. Hu M, Lee W, Jiao J, Li X, Gibbons DE, Hassan CR, Tian GW, Qin YX (2019): Mechanobiological modulation of in situ and in vivo osteocyte calcium oscillation by acoustic radiation force. Physiological Res. Ann NY Acad Sci. Oct 23, doi: 10.1111/nyas.14262. PMID: 31646646
  122. Wang HH, Wang K, Deng Z, Li XF, Qin YX, Zhan HS, Niu WX (2019): Effects of facet joint degeneration on stress alterations in cervical spine C5-C6: A finite element analysis. Math Biosci Eng. Physiological Res. Aug 14;16(6):7447-7457. PMID: 31698622
  123. Su Y, Cockerill I, Zheng Y, Tang L, Qin YX, Zhu D (2019): Interfacial zinc phosphate is the key controlling biocompatibility of metallic zinc implants. Bioact Mater. 2019 May 20;4:196-206, PMID: 31193406
  124. Fu J, Su Y, Qin YX, Zheng Y, Wang Y, Zhu D (2020): Evolution of metallic cardiovascular stent materials: A comparative study among stainless steel, magnesium and zinc. 2020 Feb;230:119641. PMID: 31806406
  125. Yi X, Wu L, Liu J, Li B, Zhou Q and Qin YX (2020): Low-intensity pulsed ultrasound protects subchondral bone in rabbit temporomandibular joint osteoarthritis by suppressing TGF-β1/Smad3 pathway. J Ortho Res. 2020 Feb 15. doi: 10.1002/jor.24628. PMID: 32060941
  126. Cockerill I, Su Y, Sinha S, Qin YX, Zheng Y, Young ML, Zhu D (2020): Porous zinc scaffolds for bone tissue engineering applications: A novel additive manufacturing and casting approach. Mater Sci Eng C Mater Biol Appl. 2020 May;110:110738. doi: 10.1016/j.msec.2020.110738. PMID: 32204047
  127. Wang Y, Zhu Y, Xue Y, Wang J, Li, X, Wu X, Qin YX, Chen W (2020): Sequential in-situ route to synthesize novel composite hydrogels with excellent mechanical, conductive, and magnetic responsive properties. Material Design. 193 (2020) 108759, https://doi.org/10.1016/j.matdes.2020.108759
  128. Yu W, Wu XG, Cen HP, GuoY, Li CX, Wang Y, Qin YX, Chen W (2020): Study on the biomechanical responses of the loaded bone in macroscale and mesoscale by multiscale poroelastic FE analysis. BioMed Eng Online. (2019) 18:122, https://doi.org/10.1186/s12938-019-0741-3
  129. Hassan CR, Lee W, Komatsu D, Qin YX (2020): Evaluation of Nucleus Pulposus Fluid Velocity and Pressure Alteration Induced by Cartilage Endplate Sclerosis using a Poro-elastic Finite Element Analysis. Biomech Model Mechanobio. https://doi.org/10.1007/s10237-020-01383-8
  130. Gao J, Su Y, Qin YX (2020): Calcium phosphate coatings enhance biocompatibility and degradation resistance of magnesium alloy: Correlating in vitro and in vivo Bioactive Materials. 6 (2021) 1223-1229. PMID:       https://doi.org/10.1016/j.bioactmat.2020.10.024
  131. He MC, Zhang J, Chen XJ, Shen YS, Fang B, Qin YX, He W, Wei QS (2020): Osteoclastic activity was associated with the development of steroid-induced osteonecrosis of femoral head. Artificial Cells, Nanomed, Biotech. 48:1, 1036-1046, DOI: 10.1080/21691401.2020.1774596, https://doi.org/10.1080/21691401.2020.1774596
  132. Wang JH, Xue YN, Wang YQ, An MW, Qin YX, Chen W (2021): High-strength and tough composite hydrogels reinforced by the synergistic effect of nano-doping and triple-network structures. European Polymer J. Online Nov. 2020, 110122. https://doi.org/10.1016/j.eurpolymj.2020.110122
  133. Wang JH, Xue YN, Wang YQ, An MW, Qin YX, Chen W (2021): Fe3+, NIR light and thermal responsive triple network composite hydrogel with multi-shape memory effect. Composites Science and Technology (accepted).
  134. Zhang G, Li X, Wu L, and Qin YX (2021): Piezo1 Channel Activation in Response to Mechanobiological Acoustic Radiation Force in Osteoblastic Cells. Bone Res 9, 16 (2021). https://doi.org/10.1038/s41413-020-00124-y
  135. Sun S, Tang L, Zhao T, Kang Y, Sun L, Liu C, Li Y, Xu F, Qin YX, Ta D (2021): Longitudinal effects of low-intensity pulsed ultrasound on osteoporosis and osteoporotic bone defect in ovariectomized rats. Ultrasounics. May 2021, Vol 113. https://doi.org/10.1016/j.ultras.2021.106360
  136. Maiorino L, Shevik M, Adrover JM, Han X, Georgas E, Wilkinson JE, Seidner H, Foerschner L, Tuveson D, Qin YX, Egeblad M (2022): Longitudinal intravital imaging through clear silicone windows. JoVE Journal. https://www.jove.com/v/62757?status=a64763k
  137. Gan Z, Guo B, Cheng J, Qin YX (2022): Design and simulation of a 2-D array flexible ultrasound transducer system for tissue characterization – A pilot study. Med Novel Tech Device. Vol 13, March 2022, 100106. https://doi.org/10.1016/j.medntd.2021.100106
  138. Wang Y, Liao J, Wu X, Zhu F, Qin YX, Chen W, Zheng Q (2022): Thermal and NIR controlled flexible switching devices using a smart conductive composite hydrogel approach. Composites Sci and Tech. Vol 222, 3 May 2022. https://doi.org/10.1016/j.compscitech.2022.109371
  139. Macaluso B, Hassan CR, Swanson DR, Nazemi A, Zaverukha E, Paulus M, Komatsu D, Qin YX (2022): Biomechanical Comparison of Krackow Repair and Percutaneous Achilles Repair System for Achilles Tendon Rupture Fixation – A Cadaveric and Finite Element Analysis (FEA) Study. Foot & Ankle Orthop. Mar 31;7(1):24730114221088502. doi: 10.1177/24730114221088502
  140. Su Y, Fu J, Lee W, Du S, Qin YX, Zheng Y, Wang Y, Zhu D (2022): Improved mechanical, degradation, and biological performances of Zn-Fe alloys as bioresorbable implants. Bioact Mater. doi: 10.1016/j.bioactmat.2021.12.030. PMID: 35386444.
  141. Yuan M, Harmett MC, Yan TH, Georgas E, Qin YX, Zhou HC, Wang Y (2022): Progress, opportunities, and challenges of magneto-plasmonic nanoparticles under remote magnetic and light stimulation for brain-tissue and cellular regeneration. Nanomaterials. 2022, 12(13), 2242; https://doi.org/10.3390/nano12132242
  142. Maiorino L, Shevik M, Adrover JM, Han X, Georgas E, Wilkinson JE, Seidner H, Foerschner L, Tuveson DA, Qin YX, Egeblad M (2022): Longitudinal Intravital Imaging Through Clear Silicone Windows. Cancer Res, Jan 5, 2022, doi: 10.3791/62757.
  143. Wang Y, Zhu Y, Zhang X, Zhu F, Qin YX, Chen W, Zheng Q (2022): Luminescent composite organohydrogels with Fe3+, pH, and glucose-dependent shape memory behavior accompanied with diverse fluorescence variation. Chem Eng. Vol 450, 26 May 2022. https://doi.org/10.1016/j.cej.2022.137930
  144. Su Y, Fu J, Zhou J, Georgas E, Du S, Qin YX, Zheng Y, Wang Y, Zhu D (2022): Blending with transition metals improves bioresorbable zinc as better medical implants. Bioact Mater. Jun 2:243-258. doi: 1016/j.bioactmat.2022.05.033. eCollection 2023 Feb. PMID: 35702610
  145. Georgas E, Yuan M, Chen J, Wang Y, Qin YX (2023): Bioactive superparamagnetic iron oxide-gold nanoparticles regulated by a dynamic magnetic field induce neuronal Ca2+ flux and differentiation. Bioactive Materials. Vol 26, page: 478-489. Aug, 2023. Front cover.
  146. Zhou J, Georgas E, Su Y, Zhou J, Kroger N, Benn F, Kopp A, Qin YX, Zhu D (2023): Evolution From Bioinert to Bioresorbable: In Vivo Comparative Study of Additively Manufactured Metal Bone Scaffolds. Adv Sci. (in press)
  147. Zhang X, Lang B, Yu W, Jia L, Zhu F, Xue Y, Wu X, Qin YX, Chen W, Wang Y, Zheng Q (2023): Magnetically induced anisotropic conductive hydrogels for multidimensional strain sensing and magnetothermal physiotherapy. Chem Eng J, Vol 474, Oct 15, 2023, 145832. org/10.1016/j.cej.2023.145832.
  148. Qin YX, Zhao J (2023): Mechanobiology in cellular, molecular, and tissue adaptation. Mechanobiology in Medicine. Vol 1, Issue 2, Dec 2023, org/10.1016/j.mbm.2023.100022
  149. Lee W, Georgas E, Komatsu D, Qin YX (2023): Daily low-intensity pulsed ultrasound stimulation mitigates joint degradation and pain in a post-traumatic osteoarthritis rat model. J Orthop Trans. (in press)

Books & Chapters

  1. Rubin, C.T., Judex, S., McLeod, K.J., Qin, Y-X (2001): Inhibition of Osteopenia by Biophysical Intervention. In: Osteoporosis. Marcus, R., Feldman, D., Kelsey, J. (eds.) 2nd edition, Academic Press, San Diego, CA.
  2. Rubin, C., Qin, Y-X & Judex, S. (2004) The Osteogenic Potential of Extremely Low Level Mechanical Signals: The Physiologic Relevance and Clinical Application of a Non-Invasive, Non-Pharmacologic Factor which is Strongly Anabolic to Bone. Biologic Mechanisms in Tooth & Skeletal Biology. 379-389. Z. Davidovitch & J. Mah, Eds.
  3. Qin, Y-X, Rubin C. (2005): Mechanotransduction and Its Role in Bone Adaptation. In “Current Topics in Bone biology and Osteoporosis.” World Scientific Publisher, ISBN 981-256-209-5.
  4. Judex, S., Boyd, S., Qin, Y-X, Miller, L., Müller, R., Rubin, C. (2003) Combining High-Resolution MicroCT with Material Composition to Define the Quality of Bone Tissue. Current Osteoporosis Reports. 1:11-19
  5. Qin, Y-X, Rubin C., Xia, Y. (2006): Bone Mechanotransduction and Its Role in Remodeling. In “Current Topics in Osteoporosis.” Chinese Academic and Science Publisher, ISBN:7040182955. June.
  6. Rubin, C., Qin, Y-X, Hadjiargyrou, M. & Judex, S. (2005) Bone’s ‘Preferred Strain History’ Provides Insight into a Proposed Common Pathway for the Stimulation of Bone Formation by Distinct Biophysical Signals. NIH/AAOS: Physical Signals in Bone. R. Aaron & M. Bolander, eds. Amer. Academy Orthopaedic Surgeons Press Ch.5:61-76.
  7. Qin, Y-X, and Mittra, E. (2006): Bone Density Measurement. In “Encyclopedia of Medical Devices and Instrumentation,” 2nd Edition, edited by J. G. Webster. John Wiley & Sons Publisher, ISBN-13 978-0-471-26358-6, Vol.1:550-558.
  8. Qin, Y-X, Lin W., Xia, Y., Mittra, E., Rubin, C., Müller, R. (2007): Non-Invasive Bone Quality Assessment Using Quantitative Ultrasound Imaging and Acoustic Parameters. In “Advanced Bioimaging Technologies in Assessment of the Quality of Bone and Scaffold Materials,” edited by L. Qin and H. Genant. Springer, ISBN: 9783540454540.
  9. Ozcivici, E., Ferreri, S., Qin, Y.X., Judex, S. (2007) Determination of bone’s mechanical matrix properties by nanoindentation. In: Molecular Methods in Medicine: Osteoporosis. Westendorf, J. (ed.). The Humana Press, Totowa, NJ.
  10. Qin, Y-X, et al. (2008): Co-Editor for “The Protocols in Musculoskeletal Research -A Practical Manual for Laboratory Techniques.” World Scientific Publisher.
  11. Rubin, C. T., Judex, S., Rubin, J. & Qin, Y-X. (2008) Inhibition of osteopenia by biophysical intervention. In: Osteoporosis, Eds: R. Marcus, J. Kelsey & D. Feldman. 3rd Edition. Academic Press, San Diego, CA.
  12. Rubin, C., Adler, B., Qin, Y-X. & Judex, S. (2007) Can Mechanical Signals Provide an Effective Countermeasure for Bone and Muscle Loss During Long-Term Spaceflight? Bioastronautics: Bone Loss in Space. P. Cavagnah, Editor.
  13. Mittra E, Yaghoubi S, Qin Y-X. (2008) MicroPET imaging of small animals. In: The Protocols in Musculoskeletal Research: A Practical Manual for Laboratory Techniques. ISBN 978-981-270-610-2, World Scientific Publisher.
  14. Qin, Y-X., Xia, Y., Lin, W., Mittra, E., Rubin, C., Gruber, B. (2008): Noninvasive Ultrasound Imaging for Bone Quality Assessment using Scanning Confocal Acoustic Diagnosis, mCT, DXA Measurements, and Mechanical Testing. Lec Notes in Comput Sci, ISSN:0302-9743 (p)/1611-3349 (online). Dec, 4901:216-233.
  15. Ferreri, S., Judex, S., Qin Y-X. (2008) Nanoindentation: Techniques and Technical Considerations for Musculoskeletal Research. In: A Practical Manual for Musculoskeletal Research: A Practical Manual for Laboratory Techniques. ISBN 978-981-270-610-2, World Scientific Publisher.
  16. Ni, Q., Nicolella, D.P., Wang, X., Nyman, J.S., Qin Y-X. (2008) The Characterization of Cortical Bone Water Distribution and Structure Changes on Age, Microdamage and Disuse by Nuclear Magnetic Resonance. In: A Practical Manual for Musculoskeletal Research: A Practical Manual for Laboratory Techniques. ISBN 978-981-270-610-2, World Scientific Publisher.
  17. Meng, Y., Qin Y-X. (2008) Stem Cells and Their Role in Bone Formation and Regeneration. In: The Protocols in Musculoskeletal Research: A Practical Manual for Musculoskeletal Research. ISBN 978-981-270-610-2, World Scientific Publisher.
  18. Lam, H.Y., Qin Y-X. (2008) Functional Disuse Model for Musculoskeletal Adaptation. In: The Protocols in Musculoskeletal Research: A Practical Manual for Musculoskeletal Research. ISBN 978-981-270-610-2, World Scientific Publisher.
  19. Yingchao Su, Yufeng Zheng, Liping Tang, Yi-Xian Qin, Donghui Zhu. Calcium phosphate coatings for orthopedic biomaterials. Orthopedic Biomaterials, editor: Bingyun Li and Thomas Webster. Springer, March 2018.
  20. Yingchao Su, Yadong Wang, Liping Tang, Yufeng Zheng, Yi-Xian Qin, Donghui Zhu. Development of Biodegradable Zn-based medical implants. Orthopedic Biomaterials, editor: Bingyun Li and Thomas Webster. Springer, March 2018.
  21. Qin YX, Hu M (2019): Biomechanics of Bone and Cartilage. Frontiers of Orthopaedics Biomechanics. Editor: CK Chen and S Woo. Wiley
  22. Qin YX, Hu M (2020): In Vivo Models of Muscle Stimulation and Mechanical Loading in Bone Mechanobiology. Mechanobiology. Editor: G Niebur. Elsevier

Intellectual Property

  1. Qin, YX: System and methods for promoting cellular activities for tissue maintenance, repair, and regeneration. PCT Patent. PCT/US16/21317. US Patent. Feb. 22, 2018. US 2018 / 0050223 A1. International: China (serial number 201680013055.3) and Hong Kong (serial number 18105777.8). US Patent Appl #15/557,268, US Patent #11,179,581 (Issued on Nov. 23, 2021)
  2. Qin, Y-X.: Combined diagnostic confocal scanning and low intensity ultrasound treatment. US Patent #US8,465,427 B1, Application # US 12/727,996, Issued Jun 18, 2013.
  3. Qin, Y-X., Lin, W. and Rubin, C.T.: Frequency Scanning of Ultrasound Attenuation as a Diagnostic to Determine Bone Physical Properties (R-7424). Patent Pending, 2001.
  4. Qin, Y-X., Lin, W. and Rubin, C.T.: Method and apparatus for scanning confocal acoustic diagnostic for bone quality (R-7450). Patent Pending (Provisional Application #60/271,957), 2001. Issued Patent # 7,727,152, June 1, 2010.
  5. Qin, Y-X., Zhu, L., Young, C. and Hsu, W.: A Transducer with Piezoelectric Foil for Measuring Forces, Chinese Patent No. 12144, 1988.
  6. Shao, Q., Qin, Y-X. and Wang, W.: The Stabilizer of Liquid Flow Velocity Used in a Flow meter for Measuring Flow Velocity and Quantity, Chinese Patent No. 1896, 1986.
  7. Qin, Y-X., Lin, W.: Phased-Array Electronic Confocal Ultrasound Scanning for Material and Tissue Quality. Disclosure #R-7682, 2003, Provisional Patent Application: 4/13/06 Serial No.: 60/791,644. PCT Application on 4/13/07.
  8. Qin, Y-X., Xia, Y. and Lin, W.: Scanning Acoustic Topology Mapping for Determining Tissue Surface Features and Wave Transmit Thickness. Disclosure #R-7681, 2003, Provisional Patent Application: 4/13/06 Serial No.: 60/791,642. PCT Application on 4/13/2007.
  9. Qin, Y-X., Xia, Y. and Lin, W.: Phased array ultrasound with electronically controlled focal points for assessing bone quality via acoustic topology and wave transmit functions. Combined serial numbers 60/791,642 and 60/791,644 (PCT application: US07/09281) filed 4/13/2007. US patent application, 12/297,089, filed on 10/13/2008.
  10. Qin, Y-X.: Combined Diagnostic Confocal Scanning and Low Intensity Ultrasound Treatment, 12/727,996. Continuation in Part application filed on 3/19/2010, claims priority to US 12/297,079.
  11. Zhu D, Qin, YX, Penna J: Bioresorbable Zinc-based Devices for Ligament or Tendon Reconstruction. Invention ID: IPR 20 034, Tech ID: 050-9120. 10-31-2019

 

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