Welcome
The primary research area focuses on functional and molecular optical imaging techniques for early disease detection and image-guided intervention in preclinical and clinical settings. For disease characterization and evaluation of intervention efficacy, there is a strong need for quantitative imaging modalities that can provide (bio)markers fast, frequently, and non-invasively. Optical / Photoacoustic imaging modalities can simultaneously quantify functional and metabolic contrasts, such as tissue blood flow, oxygenation, and oxygen metabolism, without the need for contrast agent administration, which is particularly attractive for early diagnosis and intraoperative evaluation in real-time. We apply these quantitative techniques for neuro monitoring, cancer imaging, and therapy monitoring, as well as for monitoring engineered 3D tissue constructs for regenerative medicine, drug delivery, and neural systems. Overall, portable, and fast multimodal technology has allowed us to study tissue noninvasively in a variety of physiological contexts in both preclinical and clinical settings.