Fluorescence Imaging
Optical imaging has unique advantages compared to other imaging modalities, including simplicity, low-cost and small size. Additionally, new developments in fluorescent molecular probes, especially “switchable” and “tumor-selective” probes have raised new directions in in vivo fluorescent molecular imaging. Since these probes fluoresce in the near-infrared (NIR) optical window, where optical absorption is very low so that light can penetrate deeply, fluorescence imaging has been successfully translated from a microscopy level to whole body small animal imaging and clinics.