An international team of scientists including David Q. Matus, PhD, and Benjamin L. Martin, PhD, in the Department of Biochemistry and Cell Biology and Stony Brook University Cancer Center researchers, have developed a new cell imaging technology combining lattice light sheet microscopy (LLSM) and adaptive optics (AO) to create high-resolution “movies” of cells in their 3D environment that also captures subcellular processes. Published in Science, the research reveals a technology that shows the phenotypic diversity within cells across different organisms and developmental stages and in conditions such as mitosis, immune processes and in metastases.
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